T.HASEGAWA CO.,LTD.

What is NANOLYS^TM

Approach to Sensitive Skin
What is NANOLYS^TM
Liposome Formation with NANOLYS^TM
Technical Challenges and Solutions of Liposomes
Efficacy of NANOLYS^TM on Skin
Efficacy of NANOLYS^TM on Hair
How to Use NANOLYS^TM

Approach to Sensitive Skin

Liposomes are Optimal for Sensitive Skin Approach

Liposomes are Nano-Capsules with the Same Structure as Cell Membranes.
The Optimal Technology to Break Out of the Sensitive Skin Loop.

What is NANOLYS^TM

Preliposome: A Precursor to Create Liposomes Amazingly Easily

What is a Liposome

A Nanotechnology Born from Drug Delivery Systems (DDS).
Forms a Nano-Sized Capsule as the Hydrophilic Part that is Water-Attractive and the Hydrophobic Part that is Oil-Attractive of Phospholipids Align Facing Each Other.
Highly Permeable Because It Consists of the Same Biological Components as the Skin, and It Exhibits High Effectiveness Due to the Sustained Release of the Active Ingredients Encapsulated Within.
Requires Advanced Technology for Development and Manufacturing, and Is Mainly Used in High-End Cosmetics.

What is NANOLYS^TM

A Precursor “Preliposome” That Allows the Creation of Highly Functional, High-Value-Added Liposomes Amazingly Easily.
NANOLYS^TM Enables Liposome Formation Through Spontaneous Dispersion, and Its Innovative Usability Allows for Application in Various Skincare Products, Haircare Products, and Body Care Products.

With NANOLYS^TM, It Is Possible to Deliver Liposome Experiences
to a Wide Range of Consumers through Various Applications.

Liposome Formation with NANOLYS^TM

Verification of Dispersions by Electron Microscope and
Particle Size Distribution Measurement

Single Lamellar Vesicles

Confirmation of Single Lamellar Vesicle Structure via Electron Microscope (cryo-TEM)

Fine and Uniform Particle Size

Confirmation of Liposome Formation with an Average Particle Size of Approximately 70nm

Liposome Formation, Which Was Previously Difficult,
Can Now Be Adjusted with High Precision and Ease Thanks to NANOLYS^TM

Technical Challenges and Solutions of Liposomes

Making Liposomes Easier and More Convenient to Use

NANOLYS^TM is an innovative solution that addresses all the technical challenges
of liposomes.

Efficacy of NANOLYS^TM on Skin

NANOLYS^TM liposomes alone improve sensitive skin.

① Reduction of Transepidermal Water Loss (TEWL) NANOLYS^TM 8.0% Aqueous Solution

② Suppression of Inflammatory Cytokine IL-1α NANOLYS^TM 4.0% Aqueous Solution

Base for sensitive skin liposome cosmetics completed with NANOLYS^TM alone
When encapsulating active ingredients, synergistic effects allow optimal design
for sensitive skin concepts